Melatonin is an endogenously produced hormone secreted by the pineal gland in humans. Nocturnal secretion of melatonin is regulated by both circadian rhythms, as well as nighttime darkness, and is thought to control the circadian pacemaker and promote sleep. Light can further suppress normal nighttime melatonin production.
Restful, quality sleep has been shown to be important for those living with migraine. Studies show that melatonin as a nutritional supplement may help those living with migraine achieve more restful sleep. Current literature examining melatonin’s efficacy in nutritional support for migraine is growing, but still limited. Melatonin can be taken once per day prior to bedtime.